My NAD+ After 60 Days Of Intermittent Fasting [22% Up] 😃😄

Hi and happy Tuesday!

NAD+ is very important for health and longevity. I wrote a post describing this, which you can find here.

On February 20 of this year, I took a NAD+ test. My result was 63 ug/gHb.

The normal range is 62-160 ug/gHb. I was therefore inside this range, yet at the very bottom.

I wanted to try to find out why my NAD+ was as low as it was. And ideally find a way to increase it.

I therefore asked donotage.org if they wanted to run an experiment, which they agreed to. 👍

These are the experiments we agreed on:

• Experiment I: Do intermittent fasting (18:6) for 60 days, and then take a new NAD+ test to see if my level has changed. My 60 days ended on April 25.

• Experiment II: On April 25, stop intermittent fasting. Instead, I have installed a blue light filter on my computer to be used 24 hours a day, and I am using blue light-blocking glasses from 18:00 every day. 60 days later, I will take a new NAD+ test.

• Experiment III: When experiment II is over, I will discontinue blue light protection and instead start taking a NAD+ supplement (probably NMN) for 60 days. At the end of the 60 days, I will take another NAD+ test.

I just received the results after Experiment I. After 60 days of intermittent fasting, this is my NAD+ score:

• 77 ug/gHb.

This is a 22% increase from my earlier test. This result is quite encouraging and moves my NAD+ towards where I want it.

Does this mean that intermittent fasting increases NAD+?

This is only one data point based on one person, so we cannot draw firm conclusions from this. But it is an indication that intermittent fasting does in fact positively impact NAD+.

While I did the intermittent fasting, I tried hard to consume about as many calories as I did before. This is very difficult, however, and I imagine I did consume perhaps 5-10% fewer calories during these 60 days of intermittent fasting.

What does science say about fasting and NAD+?

Several research studies have demonstrated that fasting / caloric restriction can increase NAD+ by 20 - 50%. Here are a few of these studies:

• Healthy Lifestyle Recommendations: Do the Beneficial Effects Originate from NAD+ Amount at the Cellular Level?

• Impact of Intermittent Fasting and/or Caloric Restriction on Aging-Related Outcomes in Adults: A Scoping Review of Randomized Controlled Trials

• Fasting Promotes the Expression of SIRT1, an NAD+-Dependent Protein Deacetylase, via Activation of PPARα in Mice

Given that a substantial amount of scientific research has demonstrated that fasting / caloric restriction can increase NAD+, my NAD+ increase of 22% seems fair.

Should you be interested in testing your own NAD+, you can use coupon code LT151 and get a 10% discount from donotage.org.

What’s next?

I have stopped intermittent fasting, and I now eat normally. I am now doing Experiment II above. I have installed a blue light filter on my computer to be used 24 hours a day, and I am using blue light-blocking glasses from 18:00 every day. 60 days later, on June 24, I will take a new NAD+ test.

Next week I will share interesting news from the longevity space.

For any new readers: I am trying to live to (at least) 151. To get there, I follow 2 main principles:

• Live a super-healthy life (based on what science deems positive for longevity)

• Measure what’s going on in my body and tune any metrics that are off to become optimal

I also summarize interesting news and stories from the longevity space. And I share everything worth sharing with you.

If you enjoyed this newsletter, I would be very grateful if you gave it a ‘like’ (the ❤️ at the top).

Have a good day,
Johan

Disclaimer: The links to donotage.org are affiliate links. Which means that if you purchase a product after clicking on the link, I may receive a payment.

Here is an overview of all the tests I have taken so far: